Chinese experts’ consensus guideline on preimplantation genetic testing of monogenic disorders

Author:

Yan Liying1ORCID,Cao Yunxia2,Chen Zi-Jiang3,Du Jie4,Wang ShuYu5,Huang Hefeng6,Huang Jin1,Li Rong1ORCID,Liu Ping1,Zhang Zhe1,Huang Yu7,Lin Ge8ORCID,Pan Hong9,Qi Hongbo10,Qian Weiping11,Sun Yun12ORCID,Wu Lingqian13ORCID,Yao Yuanqing14,Zhang Bo15,Zhang Cuilian16,Zhao Shuyun17,Zhou Canquan18,Zhang Xue19ORCID,Qiao Jie1ORCID

Affiliation:

1. Department of Obstetrics and Gynecology, Center for Reproductive Medicine, National Clinical Research Center for Obstetrics and Gynecology, Peking University Third Hospital , Beijing, China

2. The First Affiliated Hospital of Anhui Medical University , Hefei, China

3. Hospital for Reproductive Medicine Affiliated to Shandong University , Jinan, China

4. Beijing Anzhen Hospital, Capital Medical University , Beijing, China

5. Beijing Obstetrics and Gynecology Hospital, Capital Medical University , Beijing, China

6. Obstetrics & Gynecology Hospital of Fudan University , Shanghai, China

7. Peking University Health Science Center , Beijing, China

8. Reproductive & Genetic Hospital of CITIC-Xiangya , Changsha, China

9. Peking University First Hospital , Beijing, China

10. The First Affiliated Hospital of Chongqing Medical University , Chongqing, China

11. Peking University Shenzhen Hospital , Shenzhen, China

12. Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine , Shanghai, China

13. The State Key Laboratory of Medical Genetics, School of Life Sciences, Central South University , Changsha, China

14. Shenzhen Key Laboratory of Fertility Regulation, The University of Hong Kong-Shenzhen Hospital , Shenzhen, China

15. Maternity and Child Health Care of Guangxi Zhuang Autonomous Region , Nanning, China

16. Henan Provincial Peoples Hospital , Zhengzhou, China

17. Hospital Affiliated to Guizhou Medical University , Guiyang, China

18. The First Affiliated Hospital, Sun Yat-sen Univeristy , Guangzhou, China

19. Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences , Beijing, China

Abstract

Abstract Recent developments in molecular biological technologies and genetic diagnostic methods, accompanying with updates of relevant terminologies, have enabled the improvements of new strategies of preimplantation genetic testing for monogenic (single gene) disorders (PGT-M) to prevent the transmission of inherited diseases. However, there has been much in the way of published consensus on PGT-M. To properly regulate the application of PGT-M, Chinese experts in reproductive medicine and genetics have jointly developed this consensus statement. The consensus includes indications for patient selection, genetic and reproductive counseling, informed consent, diagnostic strategies, report generation, interpretation of results and patient follow-ups. This consensus statement serves to assist in establishment of evidence-based clinical and laboratory practices for PGT-M.

Funder

National Natural Science Foundation of China

Publisher

Oxford University Press (OUP)

Subject

Obstetrics and Gynecology,Rehabilitation,Reproductive Medicine

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3