Differential proteomic analysis of endometrial fluid suggests increased inflammation and impaired glucose metabolism in non-implantative IVF cycles and pinpoints PYGB as a putative implantation marker

Author:

Azkargorta Mikel1ORCID,Escobes Iraide1,Iloro Ibon1,Osinalde Nerea2,Corral Blanca3,Ibañez-Perez Jone3,Exposito Antonia3,Prieto Begoña34,Elortza Felix1,Matorras Roberto34

Affiliation:

1. Proteomics Platform, CIC bioGUNE, CIBERehd, ProteoRed-ISCIII, Bizkaia Science and Technology Park, Derio, Spain

2. Department of Biochemistry and Molecular Biology, University of the Basque Country, UPV/EHU, Vitoria-Gasteiz, Spain

3. Human Reproduction Unit, Cruces University Hospital, Biocruces, University of the Basque Country, Bilbao, Spain

4. Instituto Valenciano de Infertilidad, IVI Bilbao, Spain

Funder

Grant for Fertility Innovation

Publisher

Oxford University Press (OUP)

Subject

Obstetrics and Gynaecology,Rehabilitation,Reproductive Medicine

Reference43 articles.

1. Dynamic of expression and localization of cannabinoid-degrading enzymes FAAH and MGLL in relation to CB1 during meiotic maturation of human oocytes;Agirregoitia;Cell Tissue Res,2016

2. Annexin-A2 as predictor biomarker of recurrent disease in endometrial cancer;Alonso-Alconada;Int J Cancer,2015

3. Endometrial fluid is a specific and non-invasive biological sample for protein biomarker identification in endometriosis;Ametzazurra;Hum Reprod,2009

4. Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis and cholangiocarcinoma;Arbelaiz;Hepatology,2017

5. Individualised proteome profiling of human endometrial tumours improves detection of new prognostic markers;Attarha;Br J Cancer,2013

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