Impact of assisted reproduction, infertility, sex and paternal factors on the placental DNA methylome

Author:

Choufani Sanaa1,Turinsky Andrei L12,Melamed Nir3,Greenblatt Ellen4,Brudno Michael125,Bérard Anick6,Fraser William D7,Weksberg Rosanna189ORCID,Trasler Jacquetta10,Monnier Patricia11,Fraser William D,Audibert François,Dubois Lise,Julien Pierre,Luo Zhong-Cheng,Michaud Jacques,Moutquin Jean-Marie,Muckle Gina,Séguin Jean,Trasler Jacquetta,Tremblay Richard Ernest,Abenhaim Haim,Bédard Marie-Josée,Bérard Anick,Bujold Emmanuel,Gagnon Robert,Girard Isabelle,Kibar Zoha,Marc Isabelle,Monnier Patricia,Simard Marie-Noelle,Pasquier Jean-Charles,Welt Michel,

Affiliation:

1. Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada

2. Centre for Computational Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada

3. Division of Maternal Fetal Medicine, Department of Obstetrics and Gynaecology Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada

4. Mount Sinai Centre for Fertility and Reproductive Health, Mount Sinai Hospital, Toronto, Ontario, Canada

5. Department of Computer Science, University of Toronto, Toronto, Ontario, Canada

6. Research Unit on Medications and Pregnancy, Research Centre, CHU Sainte-Justine, and Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada

7. Department of Obstetrics and Gynecology, Université de Sherbrooke and Centre de Recherche du CHUS, Sherbrooke, Quebec, Canada

8. Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, Toronto, Ontario, Canada

9. Department of Pediatrics and Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada

10. Departments of Pediatrics, Human Genetics and Pharmacology & Therapeutics, and The Montreal Children’s Hospital and Research Institute of the McGill University Health Centre

11. MUHC Reproductive Centre, Department of Obstetrics and Gynecology, Royal Victoria Hospital and Research Institute of McGill University Health Centre, Quebec, Canada

Funder

Canadian Institutes of Health Research

Natural Sciences and Engineering Research Council of Canada

Mount Sinai Department of Obstetrics and Gynaecology’s Research Fund

Canadian Centre for Computational Genomics

Geothermal Technologies Program

Genome Canada

Ontario Genomics Institute

Publisher

Oxford University Press (OUP)

Subject

Genetics(clinical),Genetics,Molecular Biology,General Medicine

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