Clinical and mechanistic differences between FK506 (tacrolimus) and cyclosporin A
Author:
Publisher
Oxford University Press (OUP)
Subject
Transplantation,Nephrology
Link
http://academic.oup.com/ndt/article-pdf/15/12/1916/25041699/151916.pdf
Reference20 articles.
1. Clipstone NA, Crabtree GR. Identification of calcineurin as a key signalling enzyme in T lymphocyte activation. Nature1992; 357: 695–697
2. Kunz J, Hall MN. Cyclosporin A, FK506, and rapamycin: more than just immunosuppression. Trends Biochem Sci1993; 18: 334–338
3. Almawi WY, Melemedjian OK, Rieder MJ. An alternate mechanism of glucocorticoid anti‐proliferative effect: promotion of a Th2 cytokine‐secreting profile. Clin Transplant1999; 13: 365–372
4. Almawi WY, Assi JW, Chudzik DM, Lazarovits AI. Opposing effects of rapamycin and cyclosporin A on activation‐induced Ca2+ release. Eur J Pharmacol1999; 381: 51–56
5. Halloran PF. Molecular mechanisms of new immunosuppressants. Clin Transplant1996; 10: 118–123
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