Does reduced cathepsin activity contribute to skin and lung fibrosis in patients with systemic sclerosis and related disorders?
Author:
Affiliation:
1. Department of Medicine, Royal Shrewsbury Hospital , Shrewsbury, UK
2. Departments of Rheumatology and Chest Medicine, James Cook University Hospital , Middlesbrough, UK
Publisher
Oxford University Press (OUP)
Subject
Pharmacology (medical),Rheumatology
Link
https://academic.oup.com/rheumatology/advance-article-pdf/doi/10.1093/rheumatology/kead549/52431881/kead549.pdf
Reference8 articles.
1. Reduced Cathepsin L expression and secretion into the extracellular milieu contribute to lung fibrosis in systemic sclerosis;Mouawad;Rheumatology,2023
2. Role of cathepsin K in the turnover of the dermal extracellular matrix during scar formation;Runger;J Invest Dermatol,2007
3. Pivotal role of cathepsin K in lung fibrosis;Bühling;Am J Pathol,2004
4. Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis;Srivastava;Respir Res,2008
5. Role for cathepsin K in emphysema in smoke-exposed Guinea pigs;Golovatch;Exp Lung Res,2009
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