The 2024 British Society for Rheumatology guideline for management of systemic sclerosis—executive summary

Author:

Denton Christopher P1ORCID,De Lorenzis Enrico2ORCID,Roblin Elen3,Goldman Nina1,Alcacer-Pitarch Begonya2ORCID,Blamont Emma4,Buch Maya H5ORCID,Carulli Maresa6,Cotton Caroline7,Del Galdo Francesco2ORCID,Derrett-Smith Emma8,Douglas Karen9,Farrington Sue4,Fligelstone Kim3,Gompels Luke10,Griffiths Bridget11,Herrick Ariane5ORCID,Hughes Michael5,Pain Clare12ORCID,Pantano Georgina13,Pauling John D14ORCID,Prabu Athiveeraramapandian8,O’Donoghue Nuala15,Renzoni Elisabetta A16,Royle Jeremy17,Samaranayaka Muditha18,Spierings Julia19,Tynan Aoife3,Warburton Louise20,Ong Voon H1ORCID

Affiliation:

1. Division of Medicine, University College London , London, UK

2. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds , Leeds, UK

3. Centre for Rheumatology, Royal Free London NHS Foundation Trust , London, UK

4. Scleroderma and Raynaud’s UK (SRUK) , London, UK

5. Department of Rheumatology, University of Manchester , Manchester, UK

6. Department of Rheumatology, Hammersmith Hospitals NHS Foundation Trust , London, UK

7. Department of Rheumatology, Liverpool University Hospitals NHS Foundation Trust , Liverpool, UK

8. Department of Rheumatology, University of Birmingham , Birmingham, UK

9. Department of Rheumatology, The Dudley Group NHS Foundation Trust , Dudley, UK

10. Department of Rheumatology, Somerset NHS Foundation Trust , Taunton, UK

11. Department of Rheumatology, Freeman Hospital , Newcastle, UK

12. Department of Rheumatology, Alder Hey Children’s Hospital , Liverpool, UK

13. Lived Experience , London, UK

14. Department of Rheumatology, North Bristol NHS Foundation Trust , Bristol, UK

15. Department of Dermatology, Salford Royal, Northern Care Alliance , Salford, UK

16. Interstitial Lung Disease Unit, Royal Brompton NHS Foundation Trust , London, UK

17. Department of Rheumatology, University Hospitals NHS Foundation Trust , Leicester, UK

18. Department of Rheumatology, Salford Royal, Northern Care Alliance , Salford, UK

19. Department of Rheumatology, University of Utrecht , Utrecht, Netherlands

20. Primary Care Sciences, Keele University , Keele, UK

Abstract

Abstract This guideline was developed according to the British Society for Rheumatology Guidelines Protocol by a Guideline Development Group comprising healthcare professionals with expertise in SSc and people with lived experience, as well as patient organization representatives. It is an update of the previous 2015 SSc guideline. The recommendations were developed and agreed by the group and are underpinned by published evidence, assessed by systematic literature review and reinforced by collective expert opinion of the group. It considers all aspects of SSc including general management, treatment of organ-based complications, including cardiopulmonary, renal and gastrointestinal tract manifestations, as well as broader impact of disease. Whilst it is focused on adults with SSc we expect that the guideline will be relevant to people of all ages and expert input and review by paediatric rheumatologists and other relevant specialists considered where the guideline was, or may not be, applicable to young people with SSc and juvenile-onset disease. In addition to providing guidance on disease assessment and management the full guideline also considers service organization within the National Health Service and future approaches to audit of the guideline. The lay summary that accompanies this abstract can be found in Supplemental information 1.

Funder

British Society for Rheumatology

Publisher

Oxford University Press (OUP)

Reference10 articles.

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