Navigating the Landscape of Translational Geroscience in Canada: A Comprehensive Evaluation of Current Progress and Future Directions-Reference-Cited by-同舟云学术

Navigating the Landscape of Translational Geroscience in Canada: A Comprehensive Evaluation of Current Progress and Future Directions

Published:2024-03-15 Issue:7 Volume:79 Page:
ISSN:1079-5006
Container-title:The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences
language:en
Short-container-title:

Author:

Hajj-Boutros Guy¹,Faust Andréa¹²,Muscedere John³⁴,Kim Perry³,Abumrad Naji⁵,Chevalier Stéphanie⁶^ORCID,Aubertin-Leheudre Mylene⁷,Bergman Howard²⁸,Bowdish Dawn⁹,Burford Jessica¹⁰,Carrington-Lawrence Stacy¹¹,Côté Hélène¹²,Dawe David E¹³¹⁴,Barreto Philipe de Souto¹⁵,Farrelly Colin¹⁶^ORCID,Fowler Robert¹⁷,Gouspillou Gilles⁷,Harrington Lea¹⁸,Lautrup Sofie¹⁹^ORCID,Howlett Susan²⁰^ORCID,Imani Mahdi²¹,Kirkland James²²,Kuchel George²³,Mallette Frédérick A²⁴²⁵,Morais José A¹^ORCID,Newman John C²⁶^ORCID,Pullman Daryl²⁷,Sierra Felipe²⁸,Van Raamsdonk Jeremy²⁹^ORCID,Watt Jennifer¹⁷^ORCID,Rylett Rebecca Jane³⁰,Duque Gustavo¹²^ORCID

Affiliation:

1. Department of Medicine, McGill University and Research Institute of the McGill University Health Centre , Montréal, Québec , Canada

2. Schouela Centre of Excellence for Sustainable Health of Seniors (Schouela CEDurable) , Montreal, Québec , Canada

3. Canadian Frailty Network , Kingston, Ontario , Canada

4. Department of Critical Care Medicine, Queen’s University , Kingston, Ontario , Canada

5. Division of Surgical Oncology and Endocrine Surgery, Department of Surgery, Vanderbilt University Medical Center , Nashville, Tennessee , USA

6. School of Human Nutrition, McGill University , Montréal , Québec , Canada

7. Département des Sciences de l’Activité Physique, Faculté des Sciences, Université du Québec à Montréal , Montréal , Québec , Canada

8. Department of Family Medicine, Faculty of Medicine and Health Sciences, McGill University , Montreal , Québec , Canada

9. Department of Pathology and Molecular Medicine, McMaster University , Hamilton, Ontario , Canada

10. Arthur Labatt Family School of Nursing, Faculty of Health Science, Western University , London, Ontario , Canada

11. Division of Aging Biology, National Institute on Aging, National Institutes of Health , Bethesda, Maryland , USA

12. Department of Pathology and Laboratory Medicine, University of British Columbia , Vancouver, British Columbia , Canada

13. Department of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba , Winnipeg , Manitoba , Canada

14. Paul Albrechtsen Research Institute, CancerCare Manitoba , Winnipeg , Manitoba , Canada

15. IHU HealthAge , CERPOP UMR 1295, Toulouse , France

16. Department of Political Studies, Queen’s University , Kingston, Ontario , Canada

17. Department of Critical Care Medicine, Sunnybrook Health Sciences Centre , Toronto, Ontario , Canada

18. Department of Biochemistry, University of Toronto , Toronto, Ontario , Canada

19. Department of Clinical Molecular Biology, University of Oslo, and Akershus University Hospital , Lørenskog , Norway

20. Department of Medicine (Geriatric Medicine), Dalhousie University , Halifax, Nova Scotia , Canada

21. Australian Institute for Musculoskeletal Science (AIMSS), Geroscience and Osteosarcopenia Research Program, University of Melbourne and Western Health , St Albans, Victoria , Australia

22. Mayo Clinic , Rochester, Minnesota , USA

23. UConn Center on Aging, University of Connecticut School of Medicine, UConn Health , Farmington, Connecticut , USA

24. Department of Medicine, Université de Montréal , Montréal, Québec , Canada

25. Maisonneuve-Rosemont Hospital Research Centre , Montréal, Québec , Canada

26. Buck Institute for Research on Aging , San Francisco, California , USA

27. Faculty of Medicine, Memorial University , St. John’s, Newfoundland , Canada

28. Hevolution Foundation , Riyadh , Saudi Arabia

29. Research Institute of the McGill University Health Centre, Montreal , Quebec , Canada

30. Department of Physiology and Pharmacology, Western University , London, Ontario , Canada

Abstract

Abstract The inaugural Canadian Conferences on Translational Geroscience were held as 2 complementary sessions in October and November 2023. The conferences explored the profound interplay between the biology of aging, social determinants of health, the potential societal impact of geroscience, and the maintenance of health in aging individuals. Although topics such as cellular senescence, molecular and genetic determinants of aging, and prevention of chronic disease were addressed, the conferences went on to emphasize practical applications for enhancing older people’s quality of life. This article summarizes the proceeding and underscores the synergy between clinical and fundamental studies. Future directions highlight national and global collaborations and the crucial integration of early-career investigators. This work charts a course for a national framework for continued innovation and advancement in translational geroscience in Canada.

Funder

Canadian Institutes of Health Research

Institute of Ageing

Canadian Frailty Network

McGill University Health Centre

Hevolution Foundation

Division of Geriatric Medicine

McGill University

Schouela CEDurable Centre of Excellence for Sustainable Health of Seniors

Publisher

Oxford University Press (OUP)

Link

https://academic.oup.com/biomedgerontology/advance-article-pdf/doi/10.1093/gerona/glae069/56976116/glae069.pdf

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