“Physiological Dysregulation” as a Promising Measure of Robustness and Resilience in Studies of Aging and a New Indicator of Preclinical Disease
Author:
Affiliation:
1. Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC
2. Groupe de recherche PRIMUS, Department of Family Medicine, University of Sherbrooke, Canada
Funder
National Institutes of Health
Publisher
Oxford University Press (OUP)
Subject
Geriatrics and Gerontology,Aging
Link
http://academic.oup.com/biomedgerontology/article-pdf/74/4/462/28074553/gly136.pdf
Reference32 articles.
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2. A novel statistical approach shows evidence for multi-system physiological dysregulation during aging;Cohen;Mech Ageing Dev,2013
3. Statistical distance as a measure of physiological dysregulation is largely robust to variation in its biomarker composition;Cohen;PLoS One,2015
4. Age differences in allostatic load: an index of physiological dysregulation;Crimmins;Exp Gerontol,2003
5. Resilience versus robustness in aging;Ukraintseva;J Gerontol A Biol Sci Med Sci,2016
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