Small extrachromosomal circular DNAs, microDNA, produce short regulatory RNAs that suppress gene expression independent of canonical promoters
Author:
Affiliation:
1. Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
Funder
NIH
Publisher
Oxford University Press (OUP)
Subject
Genetics
Link
http://academic.oup.com/nar/article-pdf/47/9/4586/28602944/gkz155.pdf
Reference44 articles.
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2. Minute chromatin bodies in malignant tumours of childhood;Cox;Lancet,1965
3. Simple procedure for isolation of satellite DNA’s from tobacco leaves in high yield and demonstration of minicircles;Wong;Biochim. Biophys. Acta,1972
4. Extrachromosomal circular DNA is common in yeast;Møller;Proc. Natl Acad. Sci. U.S.A.,2015
5. Normal and cancerous tissues release extrachromosomal circular DNA (eccDNA) into the circulation;Kumar;Mol. Cancer Res.,2017
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