Loss of cerebellar glutamate transporters EAAT4 and GLAST differentially affects the spontaneous firing pattern and survival of Purkinje cells-Reference-Cited by-同舟云学术

Loss of cerebellar glutamate transporters EAAT4 and GLAST differentially affects the spontaneous firing pattern and survival of Purkinje cells

Published:2018-05-08 Issue:15 Volume:27 Page:2614-2627
ISSN:0964-6906
Container-title:Human Molecular Genetics
language:en
Short-container-title:

Author:

Perkins Emma M¹,Clarkson Yvonne L¹,Suminaite Daumante¹,Lyndon Alastair R²,Tanaka Kohichi³,Rothstein Jeffrey D⁴,Skehel Paul A¹,Wyllie David J A¹⁵,Jackson Mandy¹

Affiliation:

1. The Centre for Discovery Brain Sciences, The University of Edinburgh, Hugh Robson Building, Edinburgh, UK

2. School of Energy, Geoscience, Infrastructure and Society, Heriot-Watt University, John Muir Building, Riccarton, Edinburgh, UK

3. Laboratory of Molecular Neuroscience, Medical Research Institute, Tokyo Medical and Dental University, Bunkyo-Ku, Tokyo, Japan

4. Department of Neurology and Neuroscience, Johns Hopkins University, School of Medicine, Baltimore, MD, USA

5. Centre for Brain Development and Repair, Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, India

Funder

Wellcome Trust

Ataxia UK

RS MacDonald Charitable Trust

Publisher

Oxford University Press (OUP)

Subject

Genetics(clinical),Genetics,Molecular Biology,General Medicine

Link

http://academic.oup.com/hmg/article-pdf/27/15/2614/25170168/ddy169.pdf

Reference79 articles.

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4. Decreased expression of glutamate transporter GLAST in Bergmann glia is associated with the loss of Purkinje neurons in the spinocerebellar ataxia type 1;Cvetanovic;Cerebellum,2015

5. Loss of β-III spectrin leads to Purkinje cell dysfunction recapitulating the behaviour and neuropathology of spinocerebellar ataxia type 5 in humans;Perkins;J. Neurosci,2010

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