Effects of polymorphisms at <i>LEP</i>, <i>CAST</i>, <i>CAPN1</i>, <i>GHR</i>, <i>FABP4</i> and <i>DGAT1</i> genes on fattening performance and carcass traits in Simmental bulls
-
Published:2017-04-11
Issue:2
Volume:60
Page:61-70
-
ISSN:2363-9822
-
Container-title:Archives Animal Breeding
-
language:en
-
Short-container-title:Arch. Anim. Breed.
Author:
Ardicli SenaORCID, Dincel Deniz, Samli Hale, Balci FarukORCID
Abstract
Abstract. The aim of this study was to investigate the effects of single nucleotide polymorphisms (SNPs) at six candidate genes (LEP, CAST, CAPN1, GHR, FABP4 and DGAT1) on fattening performance and carcass traits of Simmental bulls in Turkey. The analysis covered a total of 81 Simmental bulls grown on a private farm that were randomly selected for their fattening period for use in this study. Genotyping was performed using the PCR-RFLP method. The S20T polymorphism at the CAST gene and the G316A polymorphism at the CAPN1 gene were associated with variation in final weight, fattening period, weight gain and average daily gain (P < 0.05). In addition, LEP A80V had a significant effect on hot and chilled carcass weight and dressing percentage (P < 0.05). There was no association between GHR S555G, FABP4 V110M and DGAT1 K232A markers with the traits analysed. These results suggested that focusing on the novel effects of LEP, CAST and CAPN1 gene polymorphisms on meat production traits might be useful for marker-assisted selection in Simmental cattle.
Publisher
Copernicus GmbH
Reference60 articles.
1. Alberti, P., Panea, B., Sanudo, C., Olleta, J., Ripoll, G., Ertbjerg, P., Christensen, M., Gigli, S., Failla, S., and Concetti, S.: Live weight, body size and carcass characteristics of young bulls of fifteen European breeds, Livest. Sci., 114, 19–30, 2008. 2. Allais, S., Journaux, L., Leveziel, H., Payet-Duprat, N., Raynaud, P., Hocquette, J. F., Lepetit, J., Rousset, S., Denoyelle, C., Bernard-Capel, C., and Renand, G.: Effects of polymorphisms in the calpastatin and mu-calpain genes on meat tenderness in 3 French beef breeds, J. Anim. Sci., 89, 1–11, 2011. 3. Banos, G., Woolliams, J., Woodward, B., Forbes, A., and Coffey, M.: Impact of single nucleotide polymorphisms in leptin, leptin receptor, growth hormone receptor, and diacylglycerol acyltransferase (DGAT1) gene loci on milk production, feed, and body energy traits of UK dairy cows, J. Dairy Sci., 91, 3190–3200, 2008. 4. Botstein, D., White, R. L., Skolnick, M., and Davis, R. W.: Construction of a genetic linkage map in man using restriction fragment length polymorphisms, Am. J. Hum. Genet., 32, 314–331, 1980. 5. Buchanan, F. C., Fitzsimmons, C. J., Van Kessel, A. G., Thue, T. D., Winkelman-Sim, D. C., and Schmutz, S. M.: Association of a missense mutation in the bovine leptin gene with carcass fat content and leptin mRNA levels, Genet. Sel. Evol., 34, 105–116, 2002.
Cited by
22 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
|
|