Abstract
Brain-computer interface (BCI) technology has progressively emerged as an influential instrument for addressing the challenges faced by individuals with neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic loateral sclerosis (ALS). This review provides a comprehensive overview of the standard BCI system and its modules, discussing their pivotal role in decoding brain signals for device control or rehabilitation purposes. It also delves into the transformative potential of BCIs in replacing or augmenting compromised CNS functionalities, specifically emphasizing their applications across various neurodegenerative disorders. Research advancements such as the application of BCIs for Alzheimer’s patients using classical conditioning and the development of deep brain stimulation technologies for Parkinson’s disease are explored. Furthermore, the review sheds light on the trajectory of BCI advancements for ALS patients, emphasizing it’s not merely as a tool for restoring lost functions but also as a holistic solution to enhance their overall quality of life. The synthesis of these discussions underscores the transformative role of BCIs in the therapeutic landscape of neurodegenerative disorders and the opportunities it offers for future research and practical applications.