Detection of Epstein-Barr virus and Hashimoto’s autoimmune in patients with a thyroid disorder

Abstract

Hypothyroidism’s most common cause is Hashimoto’s thyroiditis (HT). Because Epstein-Barr virus is a common pathogen that causes autoimmune diseases to be prevalent worldwide and because it stays in the body for the duration of life, which explains why autoimmune diseases have a chronic course and are frequently accompanied by symptomatic exacerbations, the aim of this research is to determine the relationship between Epstein-Barr virus (EBV) and Hashimoto’s autoimmune disease in patients with a thyroid disorder. 120 samples were collected from the governorate of Najaf (60 with thyroidectomy and 60 as controls) to identify the presence of EBV. The proportion of patients with EBV was 27 (45%) compared to the control group, which was all negative. This study detects the autoimmune disease (Hashimoto thyroiditis) in all 160 samples using the anti-thyroperoxidase (TPO) test, which yields a positive result in 40% of patients (24), a negative result in 60% (36), and a negative result in 100% (60) of control samples.