Possibility of Nanocolloid Radiopharmaceutical Using for the Visualization of Sentinel Lymph Nodes in Patients with Gastric Cancer

Author:

Sinilkin Ivan1,Chernov Vladimir1,Afanas’ev Sergey2,Titskaya Anna1,Zelchan Roman1

Affiliation:

1. National Research Tomsk Polytechnic University

2. Cancer Research Institute Cancer

Abstract

We study the possibilities of radionuclide methods of research for identification of sentinel lymph nodes (SLN) in gastric cancer. As a result of the intraoperative radiometric research the SLN were identified in all 48 patients. The study of distant lymph nodes reveals the presence of a metastatic lesion of SLN in 27 patients (56.2 %). In 21 patients (43.8 %) there was no metastatic lesion of SLN. Intraoperative radiometric indication allows to determine the "sentinel" lymph nodes with a sensitivity of 100% and a specificity of 100%. The study of "sentinel" lymph nodes is indicated for patients with depth of invasion of T1-T2 and tumor size of less than 3 cm.

Publisher

Trans Tech Publications, Ltd.

Subject

General Engineering

Reference19 articles.

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2. S.G. Afanas'ev, V.I. Chernov, A.V. Avgustinovich, I.G. Sinilkin, The diagnostic method of sentinel lymph nodes in gastric cancer, RU Patent No 2354288 (2009) (Russian).

3. M.I. Davydov, E.M. Aksel', N.N. Blokhin, Cancer morbidity, J. of Rus. Cancer Res. Center RAMS. 18 (2) (2007) 52-89 (Russian).

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