Using Nanotech Radiopharmaceutical for the Visualization of Sentinel Lymph Nodes in Patients with Larynx and Hypopharynx Cancer-Reference-Cited by-同舟云学术

Using Nanotech Radiopharmaceutical for the Visualization of Sentinel Lymph Nodes in Patients with Larynx and Hypopharynx Cancer

Published:2015-01 Issue: Volume:1084 Page:545-548
ISSN:1662-8985
Container-title:Advanced Materials Research
language:
Short-container-title:AMR

Author:

Sinilkin Ivan¹,Chernov Vladimir¹,Choynzonov Evgeny T.²,Chijevskaya Svetlana²,Titskaya Anna¹,Zelchan Roman¹

Affiliation:

1. Tomsk Polytechnic University

2. Siberian Вranch of the Russian Academy of Medical Sciences

Abstract

The study included 17 patients. All patients with cancer of larynx and hypopharynx were injected with nanocolloid labeled with 99mTc. In total 22 lymph nodes are identified. In the study of distant sentinel lymph nodes the presence of metastatic disease was revealed in 2 patients (11.8%). In 15 patients (88.2%) there was no metastatic lesion of SLN, and nodal disease progression was not recorded during further observation. Thus, in our study we did not observe the phenomenon of the so-called "jumping" metastases. Single-photon emission computed tomography and intraoperative radiometric display allow determining the “sentinel” lymph nodes after subserous administration of radioactive colloid with a sensitivity of 100% and a specificity of 100%.

Publisher

Trans Tech Publications, Ltd.

Subject

General Engineering

Link

https://www.scientific.net/AMR.1084.545.pdf

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