Simulation of Vacuum Rotating Dryer to Dry Caffeine Colloid-Reference-Cited by-同舟云学术

Simulation of Vacuum Rotating Dryer to Dry Caffeine Colloid

Published:2012-08 Issue: Volume:560-561 Page:1159-1164
ISSN:1662-8985
Container-title:Advanced Materials Research
language:
Short-container-title:AMR

Author:

Zhu Zhao You¹,Lv Zhong Ze¹,Wang Ying Long¹,Liu Ying¹

Affiliation:

1. Qingdao University of Science and Technology

Abstract

It is time-consuming to dry the caffeine colloid got from caffeine methylation liquid after evaporating crystallization and cooling crystallization. To solve this problem, the laboratory equipment is designed to simulate vacuum rotating dryer to dry the caffeine colloid. Through the single-factor experiment and orthogonal experiment, the suitable dry conditions are determined as follows: the heating temperature is 110 °C; the vacuum degree is 0.09 MPa; the stirring speed is 250 rpm. The drying time under the optimal process conditions is reduced to 1.01hours.

Publisher

Trans Tech Publications, Ltd.

Subject

General Engineering

Link

https://www.scientific.net/AMR.560-561.1159.pdf

Reference9 articles.

1. Z.C. Huang, Z.W. Liu, Study on Synthetic Unit Reaction and Methods of Caffeine, Chem. Prod. Tech. 6 (1999) 27-32.

2. X.E. Hu, W.Z. Dai, X.J. Wang, Z.J. Guo, B.Q. Liao, R.S. Bai, Study of Extraction Process of Caffeine by Chloroform, J. Tsinghua. Unives. (Sci. Tech). 35 (1995) 13-19.

3. Z.Y. Zhu, Z.Z. Lv, Y.L. Wang, J. Gao, P. Z Cui, Measurement and Correlation for Solubility of Sodium Methyl Sulfate in Water, Ethanol, Chloroform and Cyclohexane, unpublished.

4. D. Skansi, S. Tomas, I. Fudic, A. Arapovic, The influence of pressure and temperature on the kinetics of vacuum drying of ketoprofen, Dry. Technol. 15 (1997) 1617–1631.

5. A. Lekhal, K.P. Girard, M.A. Brown, S. Kiang, J.G. Khinast, B.J. Glasser, The effect of agitated drying on the morphology of L-threonine (needle-like) crystals, Int. J. Pharmaceut. 270 (2004) 263–277.