Sol-Gel Synthesis and Characterization of SiO2-CaO-P2O5-SrO Bioactive Glass: In Vitro Study-Reference-Cited by-同舟云学术

Sol-Gel Synthesis and Characterization of SiO₂-CaO-P₂O₅-SrO Bioactive Glass: In Vitro Study

Published:2014-11 Issue: Volume:631 Page:30-35
ISSN:1662-9795
Container-title:Key Engineering Materials
language:
Short-container-title:KEM

Author:

Solgi S.¹,Shahrezaee M.²,Zamanian A.³,Jafarzadeh Kashi T.S.⁴,Raz Majid⁵,Khoshroo K.⁶,Tahriri M.⁶

Affiliation:

1. University of Tehran

2. AJA University of Medical Science

3. Materials and Energy Research Center

4. Tehran University of Medical Sciences

5. Amirkabir University of Technology (Tehran Polytechnic)

6. Tehran University of Medical Sciences (TUMS)

Abstract

Bioactive glass of the type CaO–SrO–P2O5–SiO2was obtained by the sol-gel processing method. Three samples containing 0 mol%, 5 mol% and 10 mol% of SrO were synthesized. The obtained bioactive glasses were characterized by the techniques such as, X-ray diffraction (XRD) and scanning electron microscope (SEM) and the effect of SrO/CaO substitution on in vitro biological properties of the synthesized glasses were evaluated and biocompatibility of the samples was measured using MTT assay. The results showed that incorporation of Sr in the obtained glass network did not result in any structural alteration of it due to the similar role of SrO compared with that of CaO. In vitro experiments with human osteosarcoma cell lines (MG-63) and MTT assay indicated that bioactive glass incorporating 5 mol% of Sr in the composition is non-toxic and revealed good biocompatibility.

Publisher

Trans Tech Publications, Ltd.

Subject

Mechanical Engineering,Mechanics of Materials,General Materials Science

Link

https://www.scientific.net/KEM.631.30.pdf

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