Affiliation:
1. Tokyo Metropolitan University
Abstract
The present paper describes spatially selective adhesion of rat phenochromocytoma (PC12) cells on micro-structured fine particles. The particles are packed hexagonally in two-dimensional arrangements by self-assembly. Incubation allows most cells to be successfully adhered to the region of self-assembled particles, while few cells are found on the rest of the glass substrate. The line-and-space structure of particles aligns the cells in straight lines. The desired location of cells can be obtained for both appropriate line width and space of particles, because they dominate a spatial selectivity of cell adhesion.
Publisher
Trans Tech Publications, Ltd.
Subject
Mechanical Engineering,Mechanics of Materials,General Materials Science
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