CONTRIBUTION OF INHERITED VARIANTS OF THE FTO (RS9939609) AND ADRB3 (RS4994) GENES TO THE RISK OF OBESITY DEVELOPMENT AMONG KUZBASS RESIDENTS-Reference-Cited by-同舟云学术

CONTRIBUTION OF INHERITED VARIANTS OF THE FTO (RS9939609) AND ADRB3 (RS4994) GENES TO THE RISK OF OBESITY DEVELOPMENT AMONG KUZBASS RESIDENTS

Published:2023-02-16 Issue: Volume: Page:
ISSN:
Container-title:Proceedings of the 1st International Congress "The Latest Achievements of Medicine, Healthcare, and Health-Saving Technologies"
language:
Short-container-title:

Author:

Yakovleva A. A.,Soboleva O. A.,Torgunakova A. V.,Ponasenko A.V.

Abstract

Objective: To study and compare the associations of FTO (rs9939609), ADRB3 (rs4994) gene polymorphisms with obesity in sick and healthy Kuzbass residents. The data of 1149 people (568 control and 581 main group) were used in this work. After statistical processing of the data, it was found that rs9939609 of FTO gene increases the risk of obesity in both healthy and atherosclerosis patients. No statistically significant associations were found in the ADRB3 gene.

Publisher

Kemerovo State University

Reference7 articles.

1. Дедов, И.И. Ожирение / И.И. Дедов [и др.] // Consilium Medicum. – 2021. – №23. – С. 311-325., Dedov, I.I. Obesity / I.I. Dedov [et al] // Consilium Medicum. 2021. No 23. pp. 311-325.

2. Алфёрова, В.И. Распространенность ожирения во взрослой популяции российской федерации (обзор литературы) / В.И Алфёрова, С.В. Мустафина // Ожирение и метаболизм. – 2022. – №1. – С. 96-105., Alfyorova V.I., Mustafina S.V. Obesity prevalence in the adult population of the Russian Federation (review of literature) / V.I. Alfyorova, S.V. Mustafina // Obesity and metabolism. 2022. No 1. pp. 96-105.

3. Метаболизм и ожирение: вклад гена рецептора лептина / К. Д. Иевлева [и др.] // Acta Biomedica Scientifica. – 2017. – Т.2, №5-1 (117). – С. 56-62., metabolism and obesity: contribution of leptin receptor gene / K.D. Ievleva [et al.] // Acta Biomedica Scientifica. 2017. Vol. 2., No. 5. pp. 56-62.

4. Chauhdary, Z. The composite alliance of FTO locus with obesity-related genetic variants / Z. Chauhdary, K. Rehman, M.S.H. Akash // Clin Exp Pharmacol Physiol. – 2021. – №48. – С. 954-965., Chauhdary, Z. The composite alliance of FTO locus with obesity-related genetic variants / Z. Chauhdary, K. Rehman, M.S.H. Akash // Clin Exp Pharmacol Physiol. 2021. No 48. pp. 954-965.

5. Xie, C. The ADRB3 rs4994 polymorphism increases risk of childhood and adolescent overweight/obesity for East Asia's population: an evidence-based meta-analysis / C. Xie [et al.] // Adipocyte. – 2020. –№9. – С. 77-86., Xie, C. The ADRB3 rs4994 polymorphism increases risk of childhood and adolescent overweight/obesity for East Asia's population: an evidence-based meta-analysis / C. Xie [et al.] // Adipocyte. 2020. No 9. pp. 77-86.