Author:
Bookwalter J. William,Selker Robert G.,Schiffer Lewis,Randall Margaret,Iannuzzi Debra,Kristofik Matthew
Abstract
✓ In a review of 38 glioblastoma patients for whom fresh tissue kinetic data were available before any therapy was instituted, no correlation between the labeling index and survival time could be statistically determined. This relationship seems entirely consistent with the published theoretical determinants of tumor behavior: that is, altered ability for growth arrest and differentiation, constantly evolving mutant sublines, genetic instability, and an ever-changing metabolic and vascular environment.
Publisher
Journal of Neurosurgery Publishing Group (JNSPG)
Cited by
32 articles.
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