A Review of Antiulcer Activity of Some Medicinal Plants-Reference-Cited by-同舟云学术

A Review of Antiulcer Activity of Some Medicinal Plants

Published:2024-08-15 Issue:8 Volume:14 Page:201-213
ISSN:2250-1177
Container-title:Journal of Drug Delivery and Therapeutics
language:
Short-container-title:J. Drug Delivery Ther.

Author:

Deshpande Mangirish^ORCID,Dighe Pearl^ORCID,Nagare Sujit^ORCID

Abstract

Peptic ulcer is a gastrointestinal disorder and with increased prevalence. Peptic ulcer is breaking of endothelial lining of stomach and exposing underlying tissues. Peptic ulcer occurs due to high secretion of acid and reduced defensive factors in stomach and duodenum. It is imbalance between aggressive and defensive factors. Non-steroidal anti-inflammatory drugs and Helicobacter pylori infection also increases the risk of peptic ulcer. Indiscriminate use of synthetic drugs leads to adverse effects and concomitant use of antibiotics potentiates drug-drug interaction thus search of drugs from natural sources especially herbs is need of hour. several herbal medicines have been evaluated for its antiulcer efficacy using several ulcer inducing models in laboratory animals. Present study aims at review of gastroprotective and ulcer healing potential medicinal herbs and compilation of data. This article is only restricted to antiulcer efficacy of the medicinal plants. This review presents information about the anti-ulcer efficacy of medicinal plants and various antiulcer models used to screen them. Keywords: Peptic ulcer, Gastric ulcer, Gastroprotective activity, Phyllanthus urinaria, Adiantum lunulatum, Ulcer healing activity

Publisher

Society of Pharmaceutical Tecnocrats

Reference82 articles.

1. 1. Balekar N, Jain DK, Dixit P V, Bhadoriya SS. "Evaluation of Antiulcer Activity of Whole Plant Extract of Malvastrum tricuspidatum in Experimental Animals". IJPT. 2012;11(2):53-59.

2. 2. Rakel R, Bope E. Conn's Current Therapy. WB Saunders Company; 2001.

3. 3. Govindarajan R, Vijayakumar M, Singh M, et al. "Antiulcer and antimicrobial activity of Anogeissus latifolia". J Ethnopharmacol. 2006;106(1):57-61. https://doi.org/10.1016/j.jep.2005.12.002 PMid:16413714

4. 4. Hoogerwerf W, Pasricha P. "Pharmacotherapy of gastric acidity,peptic ulcers and gastroesophageal reflux disease. In: Brunton L, Lazo J, Parker K, eds. Goodman & Gilman's The Pharmacological Basis of Therapeutics". 11th ed. McGraw-Hill Medical Publishing Division; 2006:967-981.

5. 5. Malagelada JR, Kuiprs EJ, Blaser MJ. "Acid peptic disease: clinical manifestations, diagnosis, treatement, and prognosis. In: Goldman L, Ausiello D", eds. Cecil Medicine. 23rd ed. PA:Saunders Elsevier; 2007.