ISOLATION AND SCREENING OF MARINE BACTERIAL ISOLATES AGAINST CLINICAL PATHOGENS

Abstract

Objective: The marine organism produce a large array of metabolites with relevants in drug discovery, these metabolites have biological activity such as antibacterial, antioxidant and antitumor. The present study was undertaken to isolate marine bacteria from the marine soil sample and were tested against clinical pathogens. Methods: The soil sample were collected in a sterile plastic sachet. The isolates were enumerated using the spread plate technique in Zobell marine agar. The ten isolated marine bacteria were tested against six clinical pathogens by the point inoculation method and agar well diffusion method. Results: Among ten bacterial isolates M5 exhibited a maximum antibacterial activity and it was identified as Pseudomonas japonica by 16S rRNA sequencing. Conclusion: It can be concluded that isolation of Marine bacterial samples can offer a numbers of microbial strains for sources of new biomolecules from Marine sources.