A CROSS-SECTIONAL STUDY OF FIXED DRUG ERUPTION OF MALE AND FEMALE GENITALIA AT A TERTIARY CARE HOSPITAL OF MIDDLE GUJARAT, INDIA

Author:

Tralsawala Krunal,BHABHOR ARTI,OZA RUTU HARSH,MAKWANA PRATIK

Abstract

Objectives: The point of this study was to introduce a progression of instances of genital lesion with fixed drug eruption, analyze the calprit drug, and distinguish the adjustment of example of medications causing them. Methods: Finding of fixed drug eruption (FDE) was upheld by a positive history and actual assessment. Information including age, site of lesion, time stretch between drug organization, and FDE improvement was gathered and investigated. Results: The most widely recognized causative medication was co-trimoxazole in 34 patients (87.17%), trailed by anti-inflammatory medicine in 2 (5.12%) patients, norfloxacin and erythromycin, each utilized by 1 patient (2.56%). A greatest number of patients had lesions on the glans penis (n=30) (76.92%). Hyperpigmented macular lesion were available in 23 patients (58.97%). The most widely recognized side effects which were introduced by the majority of the patients were pruritus (n=29) (74.35%), trailed by a consuming sensation (n=25) (64.10%). Conclusion: We would like to conclude that co-trimoxazole was the main causative agents of FDE and the most common site was Glans penis in male and in females Vagina and Vulva was the most common site.

Publisher

Innovare Academic Sciences Pvt Ltd

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology

Reference14 articles.

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2. Revuz J, Allanore LV. Drug reactions. In: Bolognia JL, Jorrizo JL, Schaffer JV, editor. Dermatology. Philadelphia, PA: Elsevier; 2012. p. 345-6.

3. Baker H. Fixed eruptions. In: Text Book of Dermatology. 3rded. Oxford: Blackwell Scientific Publications; 1979. p. 1121-2.

4. Shiohara T, Mizukawa Y. Fixed drug eruption: A disease mediated by self-inflicted responses of intraepidermal T cells. Eur J Dermatol 2007;17:201-8. doi: 10.1684/ejd.2007.0149, PMID 17478380

5. Baker H. Fixed Eruptions. Text Book of Dermatology. 3rd ed. Oxford: Blackwell Scientific Publications; 1979. p. 1121-2.

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