Persistent α-Fetoprotein Elevation in Healthy Adults and Mutational Analysis of α-Fetoprotein Promoter, Enhancer, and Silencer Regions

Author:

Jeon Yejoo1,Choi Yun Suk1,Jang Eun Sun1,Kim Jin Wook1,Jeong Sook-Hyang1

Affiliation:

1. Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea

Funder

Seoul National University Hospital(SNUH)

Publisher

The Editorial Office of Gut and Liver

Subject

Gastroenterology,Hepatology

Reference17 articles.

1. Hereditary persistence of alpha-fetoprotein

2. Houwert, AC, Giltay, JC, Lentjes, EG, and Lock, MT (2010). Hereditary persistence of alpha-fetoprotein (HPAF P): review of the literature. Neth J Med. 68, 354-358.

3. Ferguson-Smith, MA, May, HM, O’Hare, E, and Aitken, DA (1983). Hereditary persistence of alphafetoprotein: a new autosomal dominant trait identified in an antenatal screening programme for spina bifida. J Med Genet. 20, 458.

4. Report of hereditary persistence of α-fetoprotein in a Spanish family: molecular basis and clinical concerns

5. Molecular mechanisms of hereditary persistence of α-fetoprotein (AFP) in two Japanese familiesA hepatocyte nuclear factor-1 site mutation leads to induction of the AFP gene expression in adult livers

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