Unraveling the <i>Tcrb</i> interactome-Reference-Cited by-同舟云学术

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Unraveling the Tcrb interactome

Published:2024-01-29 Issue:2 Volume:221 Page:
ISSN:0022-1007
Container-title:Journal of Experimental Medicine
language:en
Short-container-title:

Author:

Ollikainen Noah¹,Sen Ranjan¹^ORCID

Affiliation:

1. National Institute on Aging 1 Laboratory of Molecular Biology and Immunology, Intramural Research Program, , Baltimore, MD, USA

Abstract

In this issue of JEM, Allyn et al. (https://doi.org/10.1084/jem.20230985) provide mechanistic insights into the nuclear organization of the Tcrb locus that permits long-range genomic rearrangements.

Funder

National Institute on Aging

Publisher

Rockefeller University Press

Link

https://rupress.org/jem/article-pdf/doi/10.1084/jem.20232265/1923420/jem_20232265.pdf

Reference10 articles.

1. Locus folding mechanisms determine modes of antigen receptor gene assembly

2. Formation of Chromosomal Domains by Loop Extrusion

3. A structural hierarchy mediated by multiple nuclear factors establishes IgH locus conformation

4. Two Forms of Loops Generate the Chromatin Conformation of the Immunoglobulin Heavy-Chain Gene Locus

5. The Self-Organizing Genome: Principles of Genome Architecture and Function

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