SLAM Family Receptors Regulate Immunity with and without SAP-related Adaptors-Reference-Cited by-同舟云学术

SLAM Family Receptors Regulate Immunity with and without SAP-related Adaptors

Published:2004-05-03 Issue:9 Volume:199 Page:1175-1178
ISSN:1540-9538
Container-title:Journal of Experimental Medicine
language:en
Short-container-title:

Author:

Veillette André¹²³

Affiliation:

1. Laboratory of Molecular Oncology, Clinical Research Institute of Montreal, Montréal, Québec, Canada H2W 1R7

2. Department of Microbiology and Immunology and Department of Medicine, McGill University, Montréal, Québec, Canada H3G 1Y6

3. Department of Medicine, University of Montréal, Montréal, Québec, Canada H3C 3J7

Abstract

Two papers describing mice deficient in signaling lymphocyte activation molecule and 2B4 represent the first accounts of immune phenotypes in animals lacking members of the SLAM family of receptors. The findings provide definitive evidence of the importance of SLAM-related receptors in the regulation of T cell, macrophage, and natural killer cell functions.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

Link

http://rupress.org/jem/article-pdf/199/9/1175/1150320/jem19991175.pdf

Reference23 articles.

1. The SLAM family of immune-cell receptors

2. The SAP and SLAM families in immune responses and X-linked lymphoproliferative disease

3. Molecular and immunological basis of X-linked lymphoproliferative disease

4. Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation

5. Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product

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