Immune-mediated vincristine-induced neuropathy: Unlocking therapies-Reference-Cited by-同舟云学术

Immune-mediated vincristine-induced neuropathy: Unlocking therapies

Published:2021-03-22 Issue:5 Volume:218 Page:
ISSN:0022-1007
Container-title:Journal of Experimental Medicine
language:en
Short-container-title:

Author:

Savelieff Masha G.¹^ORCID,Feldman Eva L.¹²^ORCID

Affiliation:

1. NeuroNetwork for Emerging Therapies, University of Michigan, Ann Arbor, MI

2. Department of Neurology, University of Michigan, Ann Arbor, MI

Abstract

Vincristine-induced peripheral neuropathy (VIPN) is a prevalent and painful complication in cancer patients that lacks effective treatments. In this issue of JEM, Starobova et al. (2021. J. Exp. Med.https://doi.org/10.1084/jem.20201452) report that VIPN is driven by innate immune system activation, a discovery that unlocks immunotherapies as potential treatments.

Funder

National Institutes of Health

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

Link

http://rupress.org/jem/article-pdf/doi/10.1084/jem.20210286/1412036/jem_20210286.pdf

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