Affiliation:
1. Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 1
Abstract
Given the aging population, it is important to better understand neurodegeneration in aging healthy people and to address the increasing incidence of neurodegenerative diseases. It is imperative to apply novel strategies to identify neuroprotective therapeutics. The study of sex differences in neurodegeneration can reveal new candidate treatment targets tailored for women and men. Sex chromosome effects on neurodegeneration remain understudied and represent a promising frontier for discovery. Here, we will review sex differences in neurodegeneration, focusing on the study of sex chromosome effects in the context of declining levels of sex hormones during aging.
Funder
National Institutes of Health
Conrad N. Hilton Foundation
Tom Sherak MS Hope Foundation
Rhoda Goetz Foundation for Multiple Sclerosis
Dunk MS Foundation
Nancy Davis Race to Erase Multiple Sclerosis Foundation
Publisher
Rockefeller University Press
Subject
Immunology,Immunology and Allergy
Cited by
13 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献