EXAMINATION OF THE L FORMS OF GROUP A STREPTOCOCCI FOR THE GROUP-SPECIFIC POLYSACCHARIDE AND M PROTEIN

Author:

Sharp John T.1,Hijmans W.1,Dienes L.1

Affiliation:

1. From the Departments of Medicine and Bacteriology of the Massachusetts General Hospital, and the Department of Medicine and the Robert W. Lovett Memorial Foundation for the Study of Crippling Disease, Harvard Medical School, Boston

Abstract

Two strains of L forms of group A streptococci were examined for group-specific polysaccharide and found to lack this substance. One of these was found to make a substance that had several properties in common with M protein. It is suggested that the absence of the cell wall polysaccharide is responsible for the lack of rigidity of the L form and that the L form of this species closely resembles protoplasts as prepared from other species.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

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