Affiliation:
1. From the Department of Pathology, College of Physicians and Surgeons, Columbia University, New York
Abstract
1. A method is described whereby toxic substances may be extracted from hemolytic streptococci with inactivated serum.
2. Such extracts contain large amounts of hemotoxin and leucocidin.
3. Their intravenous injection into mice causes marked hemoglobinuria, anemia, and death.
4. There is evidence that this anemia is not the only cause of death of these animals.
5. Incomplete work seems to indicate that the hemotoxin and the lethal poisons are not antigenic.
6. Certain biological properties of the extract are described.
Publisher
Rockefeller University Press
Subject
Immunology,Immunology and Allergy
Cited by
48 articles.
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