THE IMMUNOLOGICAL PROPERTIES OF THE HETEROPHILE ANTIGEN AND SOMATIC POLYSACCHARIDE OF PNEUMOCOCCUS

Author:

Goebel Walther F.1,Adams Mark H.1

Affiliation:

1. From the Hospital of The Rockefeller Institute for Medical Research

Abstract

1. The lipocarbohydrate or F polysaccharide derived from a rough variant of Type I pneumococcus (I R) is antigenic in rabbits and gives rise to precipitins and sheep cell hemolysins. The somatic or C carbohydrate on the other hand is not antigenic. 2. Antisera for the rough variant of Type 1 pneumococcus contain also bacterial agglutinins immunologically unrelated to the C and F precipitins and the heterophile antibody. 3. A study has been made of the quantitative precipitin reaction of the C and F polysaccharides in the serum of rabbits immunized with the IR pneumococcus clarifying certain of these relationships.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

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1. Dendronan;Handbook of Hydrocolloids;2021

2. Introduction to natural polysaccharides;Functional Polysaccharides for Biomedical Applications;2019

3. Lipoteichoic Acid Synthesis and Function in Gram-Positive Bacteria;Biogenesis of Fatty Acids, Lipids and Membranes;2019

4. Puzzling Over the Pneumococcal Pangenome;Frontiers in Microbiology;2018-10-30

5. Lipoteichoic Acid Synthesis and Function in Gram-Positive Bacteria;Biogenesis of Fatty Acids, Lipids and Membranes;2017

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