SEQUENTIAL CELLULAR CHANGES PRODUCED BY TYPES 5 AND 7 ADENOVIRUSES IN HELA CELLS AND IN HUMAN AMNIOTIC CELLS

Author:

Boyer Georgiana S.1,Denny Floyd W.1,Ginsberg Harold S.1

Affiliation:

1. From the Departments of Preventive Medicine, Medicine and Pediatrics, School of Medicine, Western Reserve University, and the University Hospitals, Cleveland

Abstract

The sequential cytological changes which develop in tissue culture cells infected with adenovirus types 5 and 7 are described and compared with those produced by adenovirus types 1, 2, 3, and 4. The evidence that is presented indicates that types 1, 2, and 5 belong to one major subdivision of the adenovirus group and types 3, 4, and 7 to another. That the host cell nucleus is the principal site of adenovirus synthesis has been confirmed by fluorescent antibody studies. They have demonstrated the occurrence of type-specific adenovirus antigen in the characteristic intranuclear inclusions and other virus-induced structures reported to contain virus-like particles or shown by electronmicroscopy.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

Cited by 91 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Fluoreszenzserologische Untersuchungen über die Vermehrung von Adenoviren des Rindes und Schweines in Zellkulturen;Zentralblatt für Veterinärmedizin Reihe B;2010-05-13

2. Die chemische Zusammensetzung des Adenovirus und seine Vermehrung in menschlichen Zellen;Zentralblatt für Veterinärmedizin Reihe B;2010-05-13

3. ADENOVIRUSES;Feigin and Cherry's Textbook of Pediatric Infectious Diseases;2009

4. Fine Structural Lesions Induced by Viruses;Novartis Foundation Symposia;2008-05-30

5. Recombinant E1-deleted adenovirus vector induces apoptosis in two lung cancer cell lines;European Respiratory Journal;1999-05

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3