Innovative opportunities of pharmakotherapy of generalized anxiety disorder

Abstract

The work shows the actual problem and proven effectiveness of treatment of generalized anxiety disorder (GAD), including its modern methods. There was an open-label, 6-week study of the efficacy, safety, and tolerability of opipramol dihydrochloride 200 mg/day to evaluate an innovative method of treatment the patients with GAD. The conducted study demonstrates the rapid and powerful anxiolytic effect of opipramol dihydrochloride in the treatment of general, mental and somatic anxiety in patients with GAD. Opipramol dihydrochloride demonstrates a reliable fast and strong vegetative-stabilizing effect in the treatment of vegetative and somatic symptoms from the cardiovascular, gastrointestinal, respiratory, genitourinary and neurological systems in the patients with GAD. Opipramol dihydrochloride is the drug of first choice in the treatment of GAD and an alternative treatment for anxiety disorders. Key words: generalized anxiety disorder, sigma receptors, opipramol, Hamilton anxiety scale