New polytetrazole synthesis and adsorption surface investigation based on sulfadiazine grafted polyimine

Abstract

The present work concentrates on synthesizing and adsorption surface investigation of polytetrazole polymer (P-T) created from polyimine (P-S) grafted with sulfadiazine drug. The prepared polymer is synthesized by mechanochemical polycondensation reaction between dialdehyde aromatic compound and diamine aromatic compound by applying appropriate polar solvent and glacial acetic acid at (78 °C) as dependent on the polymerization reaction. The synthetic route to prepare tetrazole polymer (P-T) consists off multi chemical reaction process, firstly the synthesis of polyimine backbone (P-S) (4-(((4'-amino-3,3'-dimethyl-[1,1'-biphenyl]-4-yl)imino)methyl)benzaldehyde) by Schiff base reaction between monomers diamine (o-tolidine) and dialdehyde (terephthalaldehyde). Secondly, is the sulfadiazine azid formation, since the conversion of sulfadiazine drug to sulfadiazine azid (4-azido-N-(pyrimidin-2-yl)benzenesulfonamide) occurred by diazonium salt formation of sulfadiazine at very low temperature (0–5 °C) and then reaction with sodium azide (NaN3) under cool conditions to convert amine group (NH2) to azide group (N3), after that sulfadiazine azide was grafted onto the polyimine backbone (P-S) by cyclization reaction process to form polytetrazole (P-T). All prepared products: sulfadiazine azide, polyimine (P-S) and polytetrazole (P-T) were characterized by FT-IR spectroscopy. Finally, the adsorption surface investigations of the prepared polymers (P-S) and (P-T) were studied for adsorption of Brilliant cresyl blue (BCB) dye. All adsorption results were recorded by using an UV-Vis spectrophotometer. Since the polytetrazole (P-T) gave very good adsorption results when applied to (BCB) dye adsorption, there can be suggestion on the polytertazole polymer applicability in many various environmental and medical applications.