Clinical Expression of Leber Hereditary Optic Neuropathy Is Affected by the Mitochondrial DNA–Haplogroup Background

Author:

Hudson Gavin,Carelli Valerio,Spruijt Liesbeth,Gerards Mike,Mowbray Catherine,Achilli Alessandro,Pyle Angela,Elson Joanna,Howell Neil,La Morgia Chiara,Valentino Maria Lucia,Huoponen Kirsi,Savontaus Marja-Liisa,Nikoskelainen Eeva,Sadun Alfredo A.,Salomao Solange R.,Belfort Rubens,Griffiths Philip,Man Patrick Yu Wai,de Coo Rene F.M.,Horvath Rita,Zeviani Massimo,Smeets Hubert J.T.,Torroni Antonio,Chinnery Patrick F.

Publisher

Elsevier BV

Subject

Genetics(clinical),Genetics

Reference34 articles.

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2. Clinical picture of LHON;Nikoskelainen;Clin Neurosci,1994

3. From genotype to phenotype in Leber hereditary optic neuropathy: still more questions than answers;Newman;J Neuroophthalmol.,2002

4. Pedigree analysis in Leber hereditary optic neuropathy families with a pathogenic mtDNA mutation;Harding;Am J Hum Genet,1995

5. Human mitochondrial diseases: answering questions and questioning answers;Howell;Int Rev Cytol,1999

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