Mutations in Two Genes Encoding Different Subunits of a Receptor Signaling Complex Result in an Identical Disease Phenotype
Author:
Publisher
Elsevier BV
Subject
Genetics(clinical),Genetics
Reference29 articles.
1. Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells;Bakker;Proc Natl Acad Sci USA,1999
2. Lipomembranous polycystic osteodysplasia (brain, bone, and fat disease): a genetic cause of presenile dementia;Bird;Neurology,1983
3. Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes;Bouchon;J Immunol,2000
4. TREM-1 amplifies inflammation and is a crucial mediator of septic shock;Bouchon;Nature,2001
5. A dap12-mediated pathway regulates expression of cc chemokine receptor 7 and maturation of human dendritic cells;Bouchon;J Exp Med,2001
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