Photocatalytic Reduction of Methyl Orange, Antibacterial and Antibreast Cancer Activities of Biogenic Silver Nanoparticle Synthesized from Beta vulgaris Extract

Abstract

Studies based on a biogenic synthesis of noble metal nanomaterials has become a promising one in today’s biomedical approach in therapy and diagnosis due to multidimensional applications. Hence, the present study is to explore the antibacterial, antibreast cancer and photocatalytic efficacy of silver nanoparticles (AgNPs) synthesized from an extract of Beta vulgaris (BV). The band at 398 nm in the UV-visible spectra confirmed the formation of AgNPs. The characteristic shift in OH and C=O peak after the formation of silver nanoparticles shows the participation of Beta vulgaris extracts in the reduction process which is further supported by from SEM morphology. The average size of the particle (17 nm) was determined from XRD analysis using Scherrer’s equation. Antibacterial results of Beta vulgaris mediated BV-AgNPs show the maximum zone of inhibition against Candida albicans. On anticancer activity, BV-AgNPs reveals the toxicity effect on the MCF-7 cell line with an IC50 value of 40.65 μg/mL. Similarly, it reduces 81.3% of methyl orange at 180 min on the photocatalytic reduction process. This study has suggested an effective replacement for the hazardous chemical methods and leads to a cost-effective, environmentally-friendly method that can also be used as antibacterial and anticancer agents.