Pharmacological and Phytochemical Assessment of Anagallis arvensis L. Leaf Extracts

Abstract

The present study elucidates anti-inflammatory potential and biochemical activity via 2,2′-diphenyl-1-picrylhydrazyl scavenging potential (DPPH), total antioxidant activity (TAA), ferric reducing antioxidant power (FRAP), ferrous chelating activity (FCA), total phenolic content (TPC), total flavonoid content (TFC) of aqua-methanol (AqM) and aqua-acetone (AqA) extracts of Anagallis arvensis L. leaf along with mineral content (AAS) and quantitative phytochemicals (FT-IR and GC-MS). AqM extract exhibited maximum anti-inflammatory activity (82.90 ± 0.91%), DPPH (65.06 ± 1.87%), TAA (46.85 ± 7.32 μg VCE/mg), FRAP (73.82 ± 1.21 μg TE/mg), TPC (104.17 ± 1.41 μg GAE/mg); while AqA showed maximum FCA (64.77 ± 1.61%) and TFC (19.12 ± 1.24 μg QE/mg). FT-IR spectra of AqM extract ranged from 1020.58 to 3853.42 cm-1. The major six phytochemicals investigated through GC-MS were 9-octadecenoic acid (Z)-methylester; 2-hexadecen-1-ol-3,7,11,15-tetramethyl- [R-[R*,R*-(E)]]; methyl elaidate; 2-methoxy-4-vinylphenol; 9-octadecenamide-(Z)-; and benzoic acid 2-hydroxy-phenylmethyl ester exhibiting antioxidant and anti-inflammatory properties. The present investigation characterizes the pharmacognostic and phytochemical profile of A. arvensis leading towards its futuristic significance in pharmaceutical and nutraceutical industries.