Practical Synthesis of 1,8-Naphthyridine-2,7-dialdehydes Syntone

Author:

Levina I.I.1,Gridnev A.A.2

Affiliation:

1. Institute of Biochemical Physics of Russian Academy of Sciences, Moscow, Russia

2. Federal Research Center of Chemical Physics of Russian Academy of Sciences, Moscow, Russia

Abstract

Several synthetic approaches for synthesizing 1,8-naphthyridines were tested. Reliable protocols for synthesis of some new 1,8-naphthyridine-2,7-dialdehydes were developed starting from 2-amino-6-methylpyridine and acetoacetate. The dialdehyde were found to react with pyrrole to form either a polymer or a macrocycle depending on conditions.

Publisher

Asian Journal of Chemistry

Subject

General Chemistry

Reference14 articles.

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4. Simple and Efficient Synthesis of 2,7-Difunctionalized-1,8-Naphthyridines

5. New heteroaromatic polyazomethines containing naphthyridine moieties: Synthesis, characterization, and biological screening

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