Synthesis and Antioxidant Evaluation of Indole Quinoline Derived Chalcones

Author:

Raithak Pranita V.1ORCID,Dhabe Arvind S.1ORCID,Atkore Sandeep T.2ORCID,Alam M. Mujahid3ORCID,Kotra Vijay4ORCID,Varala Ravi5ORCID

Affiliation:

1. Department of Botany, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad-431004, India

2. Department of Biochemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad-431004, India

3. Department of Chemistry, College of Science, King Khalid University, PO Box 9004, Abha 61413, Saudi Arabia

4. Faculty of Pharmacy, Quest International University, 30250 Ipoh, Perak, Malaysia

5. Scrips Pharma, Mallapur, Hyderabad-500076, India

Abstract

A series of novel indole quinoline derived chalcones were synthesized using cost-effective synergetic catalytic system consisting of heterogeneous basic bleaching earth clay (pH 12.5) and PEG-400 as solvent at ambient temperature with the yields of 60-76%. All these chalcones were characterized by spectral data. Both the DPPH and SOR scavenging assays were performed to evaluate their antioxidant nature of these compounds.

Publisher

Asian Journal of Chemistry

Subject

General Chemistry

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