Using an analogous monoclonal antibody to evaluate the reproductive and chronic toxicity potential for a humanized anti-TNFa monoclonal antibody
Author:
Affiliation:
1. Centocor, Inc., 200 Great Valley Parkway, Malvern, Pennsylvania 19355, USA
Publisher
SAGE Publications
Subject
Health, Toxicology and Mutagenesis,Toxicology,General Medicine
Link
http://journals.sagepub.com/doi/pdf/10.1191/096032700678815765
Reference6 articles.
1. Construction and initial characterization of a mouse-human chimeric anti-TNF antibody
2. A Short-Term Study of Chimeric Monoclonal Antibody cA2 to Tumor Necrosis Factor α for Crohn's Disease
3. Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor ? monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis
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