1. School of Clinical Medical Sciences and School of Population and Health Sciences, University of Newcastle upon Tyne and North Tyneside General Hospital, Northumbria Healthcare Trust, Newcastle upon Tyne, UK
2. School of Clinical Medical Sciences and School of Population and Health Sciences, University of Newcastle upon Tyne, UK
3. School of Clinical Medical Sciences, University of Newcastle upon Tyne and North Tyneside General Hospital, Northumbria Healthcare Trust, Newcastle upon Tyne, UK
4. School of Population and Health Sciences, University of Newcastle upon Tyne, UK
5. North Tyneside General Hospital, Northumbria Healthcare Trust, Newcastle upon Tyne, UK