1. Department of Veterinary Pharmacology, Graduate School of Agriculture and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan
2. Department of Clinical Research, Oriental Medicine Research Center, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8642, Japan
3. Primetech Life Science Laboratory, PRIMETECH Corporation, 1-3-25 Koishikawa, Bunkyo-ku, Tokyo 112-0002, Japan