Severe Insulin Resistance and Moderate Glomerulosclerosis in a Minipig Model Induced by High-Fat/ High-Sucrose/ High-Cholesterol Diet
Author:
Affiliation:
1. Institute of Cardiovascular Research, School of Life Sciences and Technology, Nanhua University
2. Medical College of Shaoguan University
3. Department of Laboratory Animal Science, Nanhua University
Publisher
Japanese Association for Laboratory Animal Science
Subject
General Veterinary,General Biochemistry, Genetics and Molecular Biology,Animal Science and Zoology,General Medicine
Link
http://www.jstage.jst.go.jp/article/expanim/56/1/56_1_11/_pdf
Reference20 articles.
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2. 2. Bonora, E., Targher, G., Alberiche, M., Bonadonna, R.C., Saggiani, F., Zenere, M.B., Monauni, T., and Muggeo, M. 2000. Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity. Diabetes Care 23: 57-63.
3. The importance of insulin resistance in the pathogenesis of type 2 diabetes mellitus
4. 4. Gross, J.L., de Azevedo, M.J., Silveiro, S.P., Canani, L.H., Caramori, M.L., and Zelmanovitz, T. 2005. Diabetic nephropathy: diagnosis, prevention, and treatment. Diabetes Care 28: 164-176.
5. 5. Huang, B.W., Chiang, M.T., Yao, H.T., and Chang, W. 2004. The effect of high-fat and high-fructose diets on glucose tolerance and plasma lipid and leptin levels in rats. Diabetes Obes. Metab. 6: 120-126.
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