Some cases of transfusion-related acute lung injury in clinical practice-Reference-Cited by-同舟云学术

Some cases of transfusion-related acute lung injury in clinical practice

Published:2015-09-30 Issue:3 Volume:22 Page:29-34
ISSN:2541-8807
Container-title:The Scientific Notes of the I. P. Pavlov St. Petersburg State Medical University
language:
Short-container-title:Uč. zap. St.-Peterbg. gos. med. univ. im. Akad. I.P. Pavlova

Author:

Bakhovadinov B. B.,Ashurova G. S.,Kucher M. A.,Tretyakova A. Y.,Khodzhiev A. B.,Khakberdiev R. M.

Abstract

Preparation of this publication was motivated by a desire to present contemporary authors look at one of the most important branches of critical care medicine - transfusion therapy and related complications, such as transfusion-related lung injury (TRALI). The article describes the causes, pathogenesis, diagnosis and therapy of TRALI patients in critical condition. In this article attention is paid to the diagnosis of TRALI, associated with transfusion of blood components, modern diagnosis criteria. The authors describe the clinical symptoms, treatment schema and propose prevention protocol of TRALI. In order to determine the incidence of TRALI in medical practice transfusion therapy data in 1900 patients was analyzed. The development of this complication was found in 12 patients, 5 patients had «possible TRALI», which is comparable with the literature data. In 5 patients and 11 donors at a laboratory study anti-leukocyte antibodies were found. The important role of prevention, based on the immune mechanisms of the pathogenesis of TRALI is marked.

Publisher

FSBEI HE I.P. Pavlov SPbSMU MOH Russia

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