Increased DNA methylation, cellular senescence and premature epigenetic aging in guinea pigs and humans with tuberculosis

Author:

Bobak Carly A.1,Abhimanyu 234,Natarajan Harini5,Gandhi Tanmay67,Grimm Sandra L.67,Nishiguchi Tomoki234,Koster Kent8,Longlax Santiago Carrero234,Dlamini Qiniso9,Kahari Jacquiline9,Mtetwa Godwin9,Cirillo Jeffrey D.8,O’Malley James110,Hill Jane E.11,Coarfa Cristian67,DiNardo Andrew R.234

Affiliation:

1. Biomedical Data Science, Geisel School of Medicine, Dartmouth College, Hanover, NH 03755, USA

2. The Global Tuberculosis Program, Baylor College of Medicine, Houston, TX 77030, USA

3. William Shearer Center for Human Immunobiology, Texas Children's Hospital, Houston, TX 77030, USA

4. Immigrant and Global Health, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA

5. Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Dartmouth College, Hanover, NH 03755, USA

6. Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA

7. Molecular and Cellular Biology Department, Baylor College of Medicine, Houston, TX 77030, USA

8. Department of Microbial Pathogenesis and Immunology, Texas A&M University Health, Bryan, TX 77807, USA

9. Baylor-Swaziland Children’s Foundation, Mbabane, Swaziland

10. The Dartmouth Institute, Dartmouth College, Hanover, NH 03755, USA

11. Department of Chemical and Biological Engineering, University of British Columbia, Vancouver, BC, Canada

Publisher

Impact Journals, LLC

Subject

Cell Biology,Aging

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