Solamargine acts as an antiviral by interacting to MZF1 and targeting the core promoter of the hepatitis B virus gene

Author:

Chen Wenwen1,Zhao Xinrui2,Huang Yingli1,Lu Kai3,Li Yuan4,Li Xiaofang1,Ding Hui1,Li Xiuling1,Sun Suofeng1

Affiliation:

1. Department of Gastroenterology, Zhengzhou University People’s Hospital, Henan Provincial People’s Hospital, Zhengzhou, Henan 450003, China

2. Master of Chinese medicine (studies and applications of internal Chinese medicines), Hong Kong Baptist University, Kowloon Tong, Hong Kong

3. Xinxiang Medical University, Clinical Medicine College, Xinxiang, Henan 453000, China

4. The Third Affiliated Hospital Affiliated of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan 450003, China

Publisher

Impact Journals, LLC

Reference35 articles.

1. Charting a new frontier in chronic hepatitis B research to improve lives worldwide. 2023. https://www.nature.com/articles/d42473-022-00044-x.

2. Hepatitis B infection in the general population of China: a systematic review and meta-analysis.;Wu;BMC Infect Dis,2019

3. Hepatitis B: treatment choice and monitoring for response and resistance.;Yuen;Expert Rev Gastroenterol Hepatol,2016

4. Overview of hepatitis B viral replication and genetic variability.;Revill;J Hepatol,2016

5. SOX9 represses hepatitis B virus replication through binding to HBV EnhII/Cp and inhibiting the promoter activity.;Wu;Antiviral Res,2020

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