Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy

Author:

An Wei12,Nadeau Scott A.12,Mohapatra Bhopal C.13,Feng Dan1,Zutshi Neha14,Storck Matthew D.1,Arya Priyanka12,Talmadge James E.4,Meza Jane L.5,Band Vimla126,Band Hamid12346

Affiliation:

1. Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE 68198, USA

2. Departments of Genetics, Cell Biology & Anatomy, University of Nebraska Medical Center, Omaha, NE 68198, USA

3. Departments of Biochemistry & Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA

4. Departments of Pathology & Microbiology, College of Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA

5. College of Public Health, University of Nebraska Medical Center, Omaha, NE 68198, USA

6. Fred & Pamela Buffet Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198, USA

Publisher

Impact Journals, LLC

Subject

Oncology

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