Country Reports on Practical Aspects of Conducting Large-Scale Community Studies of the Tolerability of Mass Drug Administration with Ivermectin/Diethylcarbamazine/Albendazole for Lymphatic Filariasis

Author:

Jambulingam Purushothaman1,Subramanian Swaminathan1,Krishnamoorthy Kaliannagounder1,Supali Taniawati2,Fischer Peter3,Dubray Christine4,Fayette Carl5,Lemoine Jean Frantz6,Laman Moses7,King Christopher8,Samuela Josaia9,Hardy Myra10,Weil Gary J.3

Affiliation:

1. 1ICMR-Vector Control Research Centre, Puducherry, India;

2. 2Universitas Indonesia, Jakarta, Indonesia;

3. 3Washington University in St. Louis, St. Louis, Missouri;

4. 4Centers for Disease Control and Prevention, Atlanta, Georgia;

5. 5IMA World Health, Pétion-Ville, Haiti;

6. 6Ministère de la Santé Publique et de la Population, Port-au-Prince, Haiti;

7. 7Papua New Guinea Institute of Medical Research, Madang, Papua New Guinea;

8. 8Case Western Reserve University, Cleveland, Ohio;

9. 9Fiji Ministry of Health and Medical Services, Suva, Fiji;

10. 10Murdoch Children’s Research Institute, Melbourne, Australia

Abstract

This article is a compilation of summaries prepared by lead investigators for large-scale safety and efficacy studies on mass drug administration of IDA (ivermectin, diethylcarbamazine, and albendazole) for lymphatic filariasis. The summaries highlight the experiences of study teams that assessed the safety and efficacy of IDA in five countries: India, Indonesia, Haiti, Papua New Guinea, and Fiji. They also highlight significant challenges encountered during these community studies and responses to those challenges that contributed to success.

Publisher

American Society of Tropical Medicine and Hygiene

Subject

Virology,Infectious Diseases,Parasitology

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