Case Report: Fatal Viscerotropic Disease in a Young Woman Following Yellow Fever Vaccination

Author:

Brunaldi Mariângela Ottoboni1,Silva René Julias Costa1,Fabro Alexandre Todorovic1,de Almeida e Araujo Daniel Cardoso2,Basile-Filho Anibal3,Auxiliadora-Martins Maria3,Menegueti Mayra Gonçalves3,Beloddi Maria Isabel3,Alves Esposito Danillo Lucas4,Lopes da Fonseca Benedito Antônio4

Affiliation:

1. 1Department of Pathology and Forensic Medicine, University Hospital, Ribeirão Preto Medical School, Universidade de São Paulo (USP), Ribeirão Preto, São Paulo, Brazil;

2. 2Division of Epidemiological Surveillance, Secretaria Municipal de Saúde, Ribeirão Preto, São Paulo, Brazil;

3. 3Division of Intensive Care Medicine, Department of Surgery and Anatomy, University Hospital, Ribeirão Preto Medical School, Universidade de São Paulo (USP), Ribeirão Preto, São Paulo, Brazil;

4. 4Infectious Diseases Division, Department of Internal Medicine, University Hospital, Ribeirão Preto Medical School, Universidade de São Paulo (USP), Ribeirão Preto, São Paulo, Brazil

Abstract

ABSTRACT. Yellow fever is a viral hemorrhagic disease, and vaccination is the most effective way to minimize the impact of the disease. Serious adverse events after yellow fever vaccination are rare. We report the case of a young woman with an unusual presentation of yellow fever 17DD vaccine-associated acute viscerotropic disease, with severe hepatic impairment following a long incubation period. She died more than a month after yellow fever vaccination.

Publisher

American Society of Tropical Medicine and Hygiene

Subject

Virology,Infectious Diseases,Parasitology

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1. 17DD-yellow-fever-vaccine;Reactions Weekly;2022-03

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